Villareal has created many site specific works including: Light Matrix (Auckland Theater Company) in Auckland, New Zealand; Volume (Frisco) at the Dallas Cowboys World Headquarters in Frisco, Texas; Buckyball at The NorthPark Center in Dallas, TX; Light Matrix (MIT) at the Massachusetts Institute of Technology, Cambridge, MA, Volume (Renwick), for the Renwick Gallery at the Smithsonian American Art Museum in Washington DC, Radiant Pathway at Rice University in Houston, Texas; Cosmos, at the Johnson Museum of Art at Cornell University, Ithaca, NY; Multiverse, The National Gallery of Art, Washington DC; Diagonal Grid, Borusan Music House, Borusan Arts, Istanbul, Turkey; Stars, Brooklyn Academy of Music, Brooklyn, New York; and Hive (Bleecker Street), for the Metropolitan Transportation Authority at the Bleecker Street subway station in Manhattan.
Villareal's work is in the permanent collections of many museums including the Albright-Knox Art Gallery, Buffalo, NY; The Museum of Modern Art, New York, NY; Naoshima Contemporary Art Museum, Kagawa, Japan; Nerman Museum of Contemporary Art, Overland Park, KS, and the National Gallery of Art, Washington, D.C.
On March 5, 2013 Villareal inaugurated The Bay Lights, a 1.8-mile-long installation of 25,000 white LED lights on San Francisco’s Bay Bridge which has since become a permanent installation.
In April 2021, Villareal completed Illuminated River, which unites 9 bridges in central London into a single, monumental work of public art.
